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Virtual screening services
Quantum is a leading company providing drug screening services in-silico and, thus, delivering to it clients strong inhibitors against variety of target-proteins
We apply our proprietary developed computational technology QUANTUM, which shows outstanding accuracy in forecasting binding affinities. The hit rate of the QUANTUM performance is about 50%, it means that a half of found in silico strong inhibitors would be confirmed in in-vitro testing!!!
Click here to download a brochure about QUANTUM hit Identification technology.
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Title: Crystal Structure of the Histone domain of Son of Sevenless |
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Functional Class: Signaling Protein Primary citation: Sondermann, H.,Soisson, S.M.,Bar-Sagi, D.,Kuriyan, J. Tandem Histone Folds in the Structure of the N-terminal Segment of the Ras Activator Son of Sevenless Structure v11 pp.1583-1593, 2003 |
Abstract Title: Tandem histone folds in the structure of the N-terminal segment of the ras activator Son of Sevenless.
Keywords: Homology, Domain, D1q9cd_, Binding, Proteins, Support, Radiation, Humans, Conformation, Histone-fold, Sevenless, Alpha, Factors,, Coli, Protein, Molecular, (homo, Dimerization, Histones, Tafs, Complementary, Models, Scattering, Histone, D1q9ca_, Sevenless, Tbp-associated, Sapiens), D1q9cc_, D1q9ce_, Data, Escherichia, Structure, Sapiens, D1q9cg_, Crystallography, Folding, Human, Light, U.s., Non-p.h.s., Proteins, Peptides, D1q9ci_, Non-u.s., Research, Acid, Sequence, Binding, D1q9ch_, Homo, D1q9cb_, Tertiary, D1q9cf_, P.h.s., Protein, Amino, Gov't, X-ray, (1q9c:a,, Prediction, Bio-effect, Combinatorial chemistry, Plant protection, Screening samples, Contract research services, Crop, Combinatorial library, Potential hits/leads, Targeted sub-array, Nearest analogs, Structural-topological characteristics, Bioeffect, Natural combinatorial chemistry, Ncc, Assay, Focused combinatorial libraries, Compounds for high throughput screening, High throughput screening, Combichem, Combinatorial, Combinatorial screening, Combinatorial screening libraries, Compound collection, Compound library, Compounds collection, Lead discovery, Libraries, Library, Focused library, Chemical library, Logs, Library, Mdl compatible database, Molecular diversity screening libraries, Molecular screening, Molecular screening libraries, Molecule, Molecules, Natural product synthesis, Organic, Parallel, Pharmacophore, Plated compounds, Plates, Potential drugs, Samples, Screening libraries, Sdf, Supplier,
