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Virtual screening services

Quantum is a leading company providing drug screening services in-silico and, thus, delivering to it clients strong inhibitors against variety of target-proteins

We apply our proprietary developed computational technology QUANTUM, which shows outstanding accuracy in forecasting binding affinities. The hit rate of the QUANTUM performance is about 50%, it means that a half of found in silico strong inhibitors would be confirmed in in-vitro testing!!!

Click here to download a brochure about QUANTUM hit Identification technology.

PDB ID: 1JYY
Title: E. COLI (lacZ) BETA-GALACTOSIDASE IN COMPLEX WITH 2-F-LACTOSE. Chains A-H, see REMARK 400.
	Functional Class: Hydrolase Primary citation: Juers, D.H.,Heightman, T.D.,Vasella, A.,McCarter, J.D.,Mackenzie, L.,Withers, S.G.,Matthews, B.W. A Structural View of the Action of Escherichia Coli (Lacz) Beta-Galactosidase Biochemistry v40 pp.14781-14794, 2001

Abstract Title: A structural view of the action of Escherichia coli (lacZ) beta-galactosidase.

Keywords: 1jyyg1, 1jyyg2, 1jyyg3, 1jyyg4, 1jyyg5, Research, Coli, Molecular, D1jyyd1, D1jyyd2, D1jyyd3, D1jyyd4, D1jyyd5, Sodium, 1jyyf5, Supersandwich, Ligands, Beta-galactosidase;, Glycosidases, 1jyyb2, Barrel, Beta-sandwich, S,s-(2-hydroxyethyl)thiocysteine, D1jyyg5, D1jyyg4, Binding, D1jyyg3, D1jyyg2, Mutarotase-like, Activity, Protein, Domain, Beta-galactosidase, 1jyyb5, D1jyyg1, Galactose-binding, Compounds, D1jyyf2, D1jyyf3, D1jyyf1, D1jyyf4, D1jyyf5, 1jyyf4, 1jyyf3, 1jyyf2, 1jyyf1, Escherichia, D1jyyh4, D1jyyh5, Immunoglobulin-like, D1jyyh1, D1jyyh2, D1jyyh3, U.s., 1jyyc4, Sandwich, Quaternary, 1jyyh1, 1jyyh3, 1jyyh2, 1jyyh5, 1jyyh4, (1jyy:a,, N-terminal, Chain, 2-fluoro-2-deoxy-lactose, D1jyyc4, 1jyya2, 1jyya3, 1jyya1, 1jyya4, 1jyya5, Domains, D1jyya5, D1jyya4, Gov't, Rolls, D1jyya1, (trans)glycosidases, Proteins, Beta-galactosidase, (a/b), Support, Beta/alpha-barrel, Activity,, Beta-glycanases, Hydrolase, Models, Beta, Metabolism, Hydrolase, Hydrolyzing, 1jyye3, Magnesium, O-glycosyl, Domain-like, Operon, Mainly, Distorted, D1jyyc1, 1jyyc5, D1jyyc3, D1jyyc2, D1jyyc5, 1jyyc1, 1jyyc2, 1jyyc3, D1jyye1, 1jyye4, 1jyye5, 1jyye2, Sites, 1jyye1, Carbohydrate, Hydrogen, Beta-galactosidase,, D1jyyb4, D1jyyb5, D1jyyb2, D1jyyb3, D1jyyb1, Beta-galactosidase/glucuronidase,, Bonding, Complex, 1jyyb3, Alpha, 1jyyb1, Structure, 1jyyb4, Galactose, 1jyyd5, 1jyyd4, 1jyyd1, Jelly, 1jyyd3, 1jyyd2, Beta, Beta-galactosidase/glucuronidase, D1jyye3, D1jyye2, Beta-galactosidase, D1jyye5, D1jyye4, D1jyya3, D1jyya2, P.h.s., Bacteria, Focused compound library, Targeted chemical collection, Pre-selected, Prescreened, Measurement, Estimation, Prediction, Hts, Uhts, High throughput screening, Ultra high-throughput screening, Development, Profiling, Hit, Lead, Hits, Leads, Drug candidate, Chemicals, Entity, Therapeutic agents, Small molecules, In vitro, Novel active compounds, Focused compound library, Targeted hit library, Entities collection, In-vitro, Vendors, Providers, Distributors, Cro, Medicinal chemists, Diverse range, Structurally diverse building blocks, Hit rich collection, Synthesized, Develop new focused arrays, Privileged scaffolds profile, Profiling, Pre-screened, Methods and principles in medicinal chemistry, Synthetic organic, Computational chemistry, Subset of, Broad variety of organic compounds, Diversity analysis, Synthetic tractability and drug like properties, Computer-aided, Optimization,